How maternal gut bacteria affect brain development in children
Investigating role of maternal gut microbiome in microglia-neuron dynamics and development of somatosensory circuits
This study is looking at how the bacteria in a mother's gut might affect her baby's brain development, especially in relation to sensory processing issues, to help us understand more about how these conditions start.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10795951 on NIH RePORTER |
What this research studies
This research investigates the influence of maternal gut microbiota on the development of brain circuits in fetuses, particularly focusing on how these microbes may impact sensory processing disorders in children. By analyzing the gene expression of microglia and using advanced imaging techniques, the study aims to uncover the mechanisms by which maternal gut health can affect fetal brain development. The research will involve both observational and experimental approaches, including the manipulation of gut microbiota in animal models to observe changes in brain development and behavior. This could lead to a better understanding of neurodevelopmental disorders and their origins.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who are interested in understanding how their gut health may influence their child's brain development.
Not a fit: Patients who are not pregnant or those whose children are already diagnosed with severe neurodevelopmental disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating neurodevelopmental disorders in children.
How similar studies have performed: Other research has shown promising results regarding the impact of maternal health on fetal development, suggesting that this approach could yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Vuong, Helen — University of Minnesota
- Study coordinator: Vuong, Helen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.