How maternal genetics influence the development of offspring
Maternal Genetic Effects Shape Developmental Evolution
This study looks at how a mother’s genes can influence the growth and development of her babies, using a tiny creature called Streblospio benedicti as a model, to help us understand more about how these genetic factors might also relate to human health and development.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10916401 on NIH RePORTER |
What this research studies
This research investigates how variations in maternal genetics affect the development of offspring, particularly focusing on the model organism Streblospio benedicti. By examining the genetic interactions between maternal and zygotic genomes, the research aims to uncover the mechanisms that lead to different developmental outcomes in offspring. The study utilizes advanced molecular and genomic tools to analyze how maternal effects can shape the evolution of developmental programs, which may have implications for understanding human health and development.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in genetic factors affecting development, particularly those with a family history of developmental disorders.
Not a fit: Patients with no interest in genetic research or those not affected by developmental issues may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of developmental biology and lead to improved health outcomes by identifying genetic factors that influence development.
How similar studies have performed: While the specific approach using Streblospio benedicti is novel, similar studies have shown that maternal genetic effects play a significant role in development, indicating potential for success.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Zakas, Christina — North Carolina State University Raleigh
- Study coordinator: Zakas, Christina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.