NIH-funded research R01 grant

How maternal blood sugar levels affect breast milk and child growth

Official title: The GROWTH Study, Glycemia Range and Offspring Weight and adiposity in response To Human milk

Funded at Lurie Children's Hospital of Chicago · NIH-11011370 · Data updated 2026-11-12

This study looks at how the sugar levels in a pregnant mom's blood can affect the nutrients in her breast milk and how that might impact her baby's growth and health, especially for moms dealing with conditions like gestational diabetes or obesity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLurie Children's Hospital of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$1,872,667
NIH project number5R01HD109260-03
Project IDNIH-11011370 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant women, particularly those with gestational diabetes or obesity, and their infants up to two years old.

Less likely to help

Patients who are not pregnant or whose children are older than two years may not benefit from this research.

What this research studies

This research investigates how the levels of sugar in a mother's blood during pregnancy influence the composition of her breast milk and, consequently, the growth and development of her child. It focuses on understanding the relationship between maternal metabolic health, particularly conditions like gestational diabetes and obesity, and the nutrients present in breast milk. By analyzing the variations in breast milk composition, the study aims to identify potential interventions that could improve health outcomes for children exposed to adverse maternal conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved nutritional guidelines for breastfeeding mothers, ultimately enhancing the health and development of their children.

How similar studies have gone: Previous research has shown that maternal health significantly impacts infant development, suggesting that this study's approach could yield valuable insights.

Where this research is happening

  • Lurie Children's Hospital of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Josefson, Jami L — Lurie Children's Hospital of Chicago
  • Study coordinator: Josefson, Jami L

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.