How maternal antibiotics affect the microbiome and metabolism of breastfeeding infants
Official title: Impact of Maternal Antibiotics on the Breastfeeding Infant Microbiome and Metabolome
Funded at University of California, San Diego · NIH-10907657 · Data updated 2026-11-12
This study is looking at how antibiotics that breastfeeding moms take can affect their babies' gut health and metabolism, using gentle skin swabs to check how much of the antibiotics get into the babies through breast milk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 10, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $338,824 |
| NIH project number | 5P50HD106463-04 |
| Project ID | NIH-10907657 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include breastfeeding mothers who are prescribed antibiotics and their infants.
✕Less likely to help
Patients who are not breastfeeding or those whose mothers have not taken antibiotics may not benefit from this research.
What this research studies
This research investigates how antibiotics taken by breastfeeding mothers influence the microbiome and metabolism of their infants. By using non-invasive skin swabs, the study aims to monitor antibiotic exposure levels in infants through breast milk. It will also analyze the impact of this exposure on the infants' microbiome and metabolic processes. The research employs advanced techniques in metabolomics and microbiome analysis to gather comprehensive data on these effects.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of antibiotic use in breastfeeding mothers, ultimately promoting healthier outcomes for infants.
How similar studies have gone: Other research has shown promising results in understanding the effects of maternal health on infant development, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Tsunoda, Shirley M — University of California, San Diego
- Study coordinator: Tsunoda, Shirley M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.