How male pesticide exposure affects reproductive health and genetics
Official title: Male pesticide exposure, reproductive health and epigenetics
Funded at Brigham and Women's Hospital · NIH-11098625 · Data updated 2026-11-12
This study is looking at how being around pesticides might affect men's reproductive health and fertility, by checking pesticide levels in urine and seeing how they relate to sperm quality and DNA changes, all to better understand how these factors could impact pregnancy and the health of future children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $667,356 |
| NIH project number | 5R01ES034700-03 |
| Project ID | NIH-11098625 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include men who are trying to conceive and may have been exposed to pesticides.
✕Less likely to help
Patients who are not of reproductive age or those without concerns related to fertility may not benefit from this research.
What this research studies
This research investigates the impact of male exposure to pesticides on reproductive health and the genetic factors that may influence fertility. It focuses on measuring pesticide levels in urine and analyzing their effects on sperm quality and DNA modifications. The study aims to understand how these exposures may affect pregnancy outcomes and the health of offspring. By examining both male and female pesticide exposure, the research seeks to uncover potential biological mechanisms linking environmental factors to fertility issues.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for male infertility, enhancing reproductive health outcomes.
How similar studies have gone: Previous research has indicated that environmental exposures can affect reproductive health, suggesting that this study's approach may yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Minguez Alarcon, Lidia — Brigham and Women's Hospital
- Study coordinator: Minguez Alarcon, Lidia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.