How lymphatic signals affect heart growth and repair
Functional roles of lymphatics in organogenesis and tissue repair
This study is looking at how special cells in the heart help it grow and heal, especially after a heart attack, and it hopes to find new ways to improve treatments for heart problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10753538 on NIH RePORTER |
What this research studies
This research investigates the role of lymphatic endothelial cells in the heart, focusing on how they produce signals that influence heart growth during development and aid in the repair process after a heart attack. By utilizing advanced animal models and molecular techniques, the study aims to uncover the mechanisms behind these lymphatic signals and their impact on cardiac health. Patients may benefit from a better understanding of heart disorders and potential new treatments that target lymphatic functions.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with a history of cardiac injuries or disorders, particularly those who have experienced a myocardial infarction.
Not a fit: Patients with non-cardiac related health issues or those under 21 years old may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies for heart diseases by enhancing cardiac repair mechanisms.
How similar studies have performed: Previous research has shown promising results in understanding lymphatic functions, suggesting that this approach could lead to significant advancements in cardiac treatment.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Oliver, Guillermo C — Northwestern University at Chicago
- Study coordinator: Oliver, Guillermo C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.