How lupus affects people over time in Midwest communities
DP22-002 Epidemiology of Lupus: Longitudinal Studies in Population-Based Cohorts - 2022
This project follows people with systemic and cutaneous lupus and matched community members over time to learn about disease course, treatments, healthcare access, and disparities.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11135288 on NIH RePORTER |
What this research studies
People with systemic lupus erythematosus (SLE) and cutaneous lupus (CLE) in a 27-county region of Minnesota and Wisconsin have their medical records linked and followed through the Rochester Epidemiology Project. The project compares those with lupus to similar people without lupus matched by age, sex, race/ethnicity, and county, and tracks diagnoses, lab results, prescriptions, and visits over time. Researchers focus on natural history, multimorbidity, opioid pain treatment, healthcare access, and disparities across the full spectrum of disease severity. This renewal continues and expands the Lupus Midwest Network (LUMEN) work to capture population-level patterns that clinic-based studies may miss.
Who could benefit from this research
Good fit: Ideal candidates are people diagnosed with SLE or CLE who live in the Rochester Epidemiology Project's 27-county region, as well as matched community members without lupus used for comparison.
Not a fit: People who live outside the REP catchment area or who are seeking experimental drug trials are unlikely to be included or receive direct benefits from this epidemiologic project.
Why it matters
Potential benefit: If successful, this work could reveal real-world patterns of lupus outcomes and care gaps that help improve diagnosis, management, and access to services for people with lupus.
How similar studies have performed: Previous population-based lupus cohort studies have improved understanding of disease patterns and care gaps, and this project builds on that established approach.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Crowson, Cynthia S — Mayo Clinic Rochester
- Study coordinator: Crowson, Cynthia S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.