How lung cancer affects immune responses to COVID-19

Who could benefit from this research

What this research studies

This research investigates how patients with lung cancer respond to COVID-19 infections and vaccinations. It focuses on understanding the immune responses of these patients, particularly how effective their immune systems are against the virus and its variants. The study collects blood samples to analyze antibody responses and other biological factors that may influence susceptibility to COVID-19. Additionally, it examines the long-term health effects of COVID-19 on lung cancer patients and the impact of different vaccination strategies.

Why it matters

Where this research is happening

• Icahn School of Medicine at Mount Sinai
  New York, United States Active

Researchers

• Principal investigator: Hirsch, Fred R — Icahn School of Medicine at Mount Sinai
• Study coordinator: Hirsch, Fred R

Related research

Other NIH-funded projects on the same topics.

• Understanding how lung cancer affects COVID-19 vulnerability through antibody analysis

  This study is looking at how lung cancer affects the way patients respond to COVID-19 and vaccines, so we can find better ways to protect them during the pandemic.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10855044

• Understanding how lung cancer affects COVID-19 vulnerability

  This study is looking at how lung cancer affects patients' ability to fight off COVID-19 and how well vaccines work for them, so we can find better ways to keep lung cancer patients safe from the virus.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10688370

• How COVID-19 infection and genes may influence memory and dementia risk

  This study looks at how getting COVID-19 and a person’s genes together affect the chance of developing memory problems and Alzheimer’s disease later in life.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11617103

• Alzheimer’s-related dementia after COVID-19: how SARS-CoV-2 affects the brain and potential drug repurposing

  This research looks at how COVID-19 may contribute to dementia by studying brain inflammation, blood vessel injury, and virus-host interactions, with the goal of finding existing drugs that could help.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11457086

• IL-22’s role in SARS-CoV-2 infection and tissue protection

  A short study to understand how the cytokine IL-22 might help protect tissues during and after COVID-19 infection, especially in people with complications related to acute graft-versus-host disease.

  NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11451891

• Maternal SARS-CoV-2 infection and its effects on placenta and child development

  This grant studies how COVID-19 infection during pregnancy might change the placenta and influence a child’s brain development, especially in kids who may be at higher genetic risk for ADHD/ASD.

  NIH research Lieber Institute, INC. · Baltimore, United States · NIH-11402254

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.