How lowering blood pressure can help prevent cognitive decline in low-income and minority patients

Effectiveness of Implementing an Intensive Blood Pressure Reduction Intervention on Cognitive Decline in Low-income and Minority Hypertensive Patients

NIH-funded research Tulane University of Louisiana · NIH-10908732

This study is looking at how lowering blood pressure can help prevent memory problems in older adults, especially those from low-income and minority backgrounds, by using friendly support and teamwork in clinics to manage their health better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTulane University of Louisiana NIH-funded
Lab location1 site (New Orleans, United States)
Project IDNIH-10908732 on NIH RePORTER

What this research studies

This research investigates the effectiveness of a targeted blood pressure reduction intervention aimed at preventing cognitive decline among low-income and minority patients, particularly those over 65. It builds on previous findings that suggest lowering systolic blood pressure to below 120 mmHg can reduce the risk of cognitive impairment. The study will implement a comprehensive strategy in real-world clinics, utilizing methods such as patient health coaching, home blood pressure monitoring, and team-based care to ensure effective management of hypertension. By focusing on African American and low-income populations, the research aims to address health disparities in cognitive health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are low-income and minority patients aged 65 and older who have hypertension.

Not a fit: Patients who do not have hypertension or are younger than 65 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of cognitive decline in vulnerable populations, improving their quality of life.

How similar studies have performed: Previous studies, such as the SPRINT trial, have shown success in using intensive blood pressure management to reduce cognitive impairment, indicating a promising approach.

Where this research is happening

New Orleans, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.