How low oxygen levels at night affect blood sugar during sleep in people living at high altitudes
Official title: Impact of Nocturnal Hypoxemia on Glucose during Sleep in High Altitude Sleep Disordered Breathing
Funded at Johns Hopkins University · NIH-10916237 · Data updated 2026-11-12
This study is looking at how low oxygen levels while you sleep might affect blood sugar control for people with sleep problems, especially those living at high altitudes, and it will also see if using extra oxygen at night can help improve blood sugar levels.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $195,806 |
| NIH project number | 5K23HL155730-03 |
| Project ID | NIH-10916237 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living at high altitudes who experience sleep disordered breathing and have concerns about their blood sugar levels.
✕Less likely to help
Patients who do not live at high altitudes or do not have sleep disordered breathing may not benefit from this research.
What this research studies
This research investigates the relationship between low oxygen levels during sleep and blood sugar control in individuals with sleep disordered breathing, particularly in high altitude populations. The study aims to understand how nocturnal hypoxemia, or low oxygen at night, contributes to glucose intolerance and diabetes. By using continuous glucose monitoring, researchers will observe changes in glucose levels in relation to oxygen levels during sleep. Additionally, the study will explore whether providing supplemental oxygen at night can improve glucose control in these patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for managing blood sugar levels in patients with sleep disordered breathing.
How similar studies have gone: While the specific approach of targeting nocturnal hypoxemia for glucose control is novel, previous studies have indicated a link between hypoxemia and glucose intolerance.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Pham, Luu Van — Johns Hopkins University
- Study coordinator: Pham, Luu Van
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.