How losing vision at different ages affects brain function and behavior
Cross modal plasticity following loss of vision at different developmental stages: Cortical function, connections and compensatory behavior
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10885016
This study looks at how the brain changes when it loses the ability to see, using short-tailed opossums to learn more about how other senses, like hearing and touch, help adapt during different stages of development.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10885016 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain adapts when vision is lost at various developmental stages. By studying the short-tailed opossum, researchers will explore changes in brain connectivity and function, particularly in areas typically responsible for processing visual information. The study aims to understand how these changes relate to behaviors that rely on other senses, such as hearing and touch. This could provide insights into the brain's remarkable ability to reorganize itself in response to sensory loss.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced vision loss at different ages, particularly children and adults.
Not a fit: Patients who have not experienced vision loss or those with other neurological conditions unrelated to sensory processing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for rehabilitation and support for individuals who have lost their vision.
How similar studies have performed: Previous studies have shown that the brain can adapt to sensory loss, but this research aims to explore these adaptations in a novel way using a specific animal model.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KRUBITZER, LEAH ANN — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: KRUBITZER, LEAH ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.