NIH-funded research R01 grant

How loneliness and feeling cut off relate to suicidal thoughts in older adults

Official title: Multimodal assessment of social disconnection as a proximal risk for suicide ideation in late life.

Funded at Rutgers, the State Univ of N.j. · NIH-11304511 · Data updated 2026-11-12

Researchers will follow people aged 65 and older for a year with frequent reports and behavioral measures to track how social disconnection and sensitivity to rejection relate to suicidal thoughts.

More Suicide research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j.
NIH-funded
Lab location1 site (Piscataway, United States)
Project startApril 1, 2025
Project endMarch 31, 2029
Funding year2026
Award (this year)$663,374
NIH project number5R01MH133713-02
Project IDNIH-11304511 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 65 or older who experience loneliness, social disconnection, recent interpersonal losses or conflicts, or past/current suicidal thoughts would be ideal candidates.

Less likely to help

People under 65, those with severe cognitive impairment that prevents completing surveys or tasks, or those not experiencing social disconnection may not be eligible or likely to benefit directly.

What this research studies

You would be asked to report your social interactions, moods, and any stressful interpersonal events frequently (for example, daily or weekly) and complete periodic questionnaires about rejection sensitivity and mood. The team will combine self-reports with behavioral measures and other social data to map when feelings of disconnection and negative events lead to suicidal thoughts. They'll look at whether people who are especially sensitive to rejection are more likely to develop suicidal thoughts after social disconnection, and whether social disconnection explains the link between negative interpersonal events and suicidal thoughts. Participation lasts about one year and involves regular check-ins and brief tasks.

Why it matters

Potential benefit: If successful, this work could help spot early warning signs and guide targeted supports to reduce suicidal thoughts among older adults.

How similar studies have gone: Prior research has linked loneliness and interpersonal stress with suicide in older adults, but few studies have used year-long, frequent monitoring, so this multimodal, intensive approach is relatively new.

Where this research is happening

  • Rutgers, the State Univ of N.j.
    Piscataway, United States
    Active

Researchers

  • Principal investigator: Cain, Nicole M — Rutgers, the State Univ of N.j.
  • Study coordinator: Cain, Nicole M

Related research

Other NIH-funded projects on the same topics.

  • Childhood suicide risk: understanding feelings and caregiver perspectives

    A multi-informant study with children aged 8-12 and their caregivers to better predict how childhood thoughts of suicide and distress develop and signal risk.

    NIH research Hunter College · New York, United States · NIH-11359696

  • Understanding childhood suicide thoughts to improve risk assessment

    This study is looking for ways to better understand and talk about suicidal thoughts in kids aged 8-12 by listening to both the children and their caregivers, using creative methods to capture their feelings and experiences, so we can help keep them safe and supported.

    NIH research Hunter College · New York, United States · NIH-11179277

  • Understanding how social disconnection affects suicide risk in older adults.

    This study is looking at how feeling lonely or rejected might affect thoughts about suicide in older adults, and it aims to understand how social connections and emotions change over time to help identify those at risk.

    NIH research Rutgers, the State Univ of N.j. · Piscataway, United States · NIH-11128041

  • How social connections can help prevent suicide thoughts in young women who love women

    This study is looking at why young women who love other women might think about suicide more than their straight friends, and it wants to find out how having strong friendships and a positive sense of self can help keep them safe, especially during big life changes like starting high school or college.

    NIH research University of Central Florida · Orlando, United States · NIH-10850599

  • Understanding why some adolescents continue to have thoughts of suicide.

    This study is looking at what helps or hinders young people in rural areas, aged 14 to 18, who have had thoughts about suicide, so we can better understand how to support them and prevent these feelings from sticking around.

    NIH research Western Kentucky University · Bowling Green, United States · NIH-10730480

  • Identifying neighborhood factors that influence youth suicide risk

    This study is looking at how things in your neighborhood might influence young people's thoughts about suicide, and it aims to find ways to make communities safer for kids and teens.

    NIH research Louisiana State Univ A&m Col Baton Rouge · Baton Rouge, United States · NIH-10665074

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.