NIH-funded research NIH-funded research

How loneliness affects drug use and HIV risk in gay and bisexual men

Official title: Dissecting the role of loneliness on substance use- and HIV-related outcomes among sexual minority men in the United States and Canada

Funded at Columbia University Health Sciences · NIH-11367303 · Data updated 2026-11-12

This project looks at whether feeling lonely contributes to using multiple drugs and to HIV-related risks among gay, bisexual, and other sexual minority men in the United States and Canada.

More Substance Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 1, 2024
Project endJuly 31, 2026
Funding year2025
Award (this year)$51,655
NIH project number5R36DA061635-02
Project IDNIH-11367303 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are gay, bisexual, and other sexual minority men living in the United States or Canada who experience loneliness or who use alcohol or other drugs.

Less likely to help

People who are not sexual minority men, who do not use substances, or whose health concerns are unrelated to loneliness may not get direct benefit from this work.

What this research studies

You would be part of work that checks whether loneliness helps explain why some sexual minority men use multiple substances or face higher HIV-related risks. The team will collect and analyze survey data and existing datasets from men in the US and Canada, looking at self-reported loneliness, patterns of substance use, and HIV-related outcomes. They may also examine social networks and compare people over time to see which social factors link to drug use and HIV risk. The goal is to identify changeable social drivers that could guide support and prevention efforts.

Why it matters

Potential benefit: If successful, the findings could point to social and mental-health targets to reduce polysubstance use, overdoses, and new HIV infections among sexual minority men.

How similar studies have gone: Previous qualitative studies hint at a link between loneliness and non-fatal overdose, but systematic, cross-national work on loneliness, polysubstance use, and HIV risk among sexual minority men is relatively new.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Marziali, Megan Elyssa — Columbia University Health Sciences
  • Study coordinator: Marziali, Megan Elyssa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.