How loneliness affects brain aging and Alzheimer's disease risk
Investigating the impact of loneliness on brain aging and pre-symptomatic Alzheimer's disease progression
This study is looking at how feeling lonely might affect the brains of older adults who are at risk for Alzheimer's disease, hoping to find clues that could help us understand and predict changes in brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mcgill University NIH-funded |
| Lab location | 1 site (Montreal, Canada) |
| Project ID | NIH-11081953 on NIH RePORTER |
What this research studies
This research investigates the relationship between feelings of loneliness and brain aging, particularly in older adults at risk for Alzheimer's disease. It aims to understand how loneliness may influence brain structure and function, potentially serving as an early indicator of cognitive decline. The study will utilize a large population data sample to analyze the effects of loneliness on brain health and identify patterns that could predict Alzheimer's progression. By examining these connections, the research seeks to uncover the underlying mechanisms linking loneliness to dementia risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those experiencing feelings of loneliness or at risk for Alzheimer's disease.
Not a fit: Patients who are not experiencing loneliness or who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or delaying Alzheimer's disease by addressing loneliness in older adults.
How similar studies have performed: Previous research has indicated a connection between loneliness and cognitive decline, suggesting that this approach may yield valuable insights into Alzheimer's disease progression.
Where this research is happening
Montreal, Canada
- Mcgill University — Montreal, Canada (Active)
Researchers
- Principal investigator: Spreng, Robert Nathan — Mcgill University
- Study coordinator: Spreng, Robert Nathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.