How lipids and food affect the absorption of oral medications and nutrients

Impact of lipids and food on oral compound absorption: mechanistic studies and modeling

NIH-funded research Northeastern University · NIH-10842902

This study is looking at how fats in food and medicines can help your body absorb important nutrients and medications better, which could lead to improved health and more effective treatments for everyone.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNortheastern University NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10842902 on NIH RePORTER

What this research studies

This research investigates how lipids found in food and drug delivery systems influence the absorption of orally taken compounds, such as medications and nutrients. By developing a modeling framework, the study aims to understand the mechanisms behind lipid interactions in the gastrointestinal tract. This could lead to improved drug formulation processes and better nutritional supplements, ultimately enhancing patient health outcomes. The research combines engineering principles with biological systems to provide insights into effective oral delivery methods.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who regularly take oral medications or supplements and are interested in understanding how food composition affects their absorption.

Not a fit: Patients who exclusively receive medications through non-oral routes, such as injections or infusions, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective oral medications and nutritional supplements, improving patient health and treatment outcomes.

How similar studies have performed: Previous research has shown promising results in understanding the role of lipids in drug absorption, indicating that this approach has potential for significant advancements.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.