How lipids and food affect the absorption of oral medications and nutrients
Official title: Impact of lipids and food on oral compound absorption: mechanistic studies and modeling
Funded at Northeastern University · NIH-10842902 · Data updated 2026-11-12
This study is looking at how fats in food and medicines can help your body absorb important nutrients and medications better, which could lead to improved health and more effective treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northeastern University NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $465,000 |
| NIH project number | 1R35GM153324-01 |
| Project ID | NIH-10842902 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who regularly take oral medications or supplements and are interested in understanding how food composition affects their absorption.
✕Less likely to help
Patients who exclusively receive medications through non-oral routes, such as injections or infusions, may not benefit from this research.
What this research studies
This research investigates how lipids found in food and drug delivery systems influence the absorption of orally taken compounds, such as medications and nutrients. By developing a modeling framework, the study aims to understand the mechanisms behind lipid interactions in the gastrointestinal tract. This could lead to improved drug formulation processes and better nutritional supplements, ultimately enhancing patient health outcomes. The research combines engineering principles with biological systems to provide insights into effective oral delivery methods.
Why it matters
Potential benefit: If successful, this research could lead to more effective oral medications and nutritional supplements, improving patient health and treatment outcomes.
How similar studies have gone: Previous research has shown promising results in understanding the role of lipids in drug absorption, indicating that this approach has potential for significant advancements.
Where this research is happening
-
Northeastern University
Boston, United States Active
Researchers
- Principal investigator: Carrier, Rebecca L — Northeastern University
- Study coordinator: Carrier, Rebecca L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.