How light-sensing proteins affect growth and body clocks
The Role of Cryptochromes in environmental regulation of growth
This project explores how light-sensing proteins called cryptochromes help living things, including humans, manage their growth and daily body rhythms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cold Spring Harbor Laboratory NIH-funded |
| Lab location | 1 site (Cold Spring Harbor, United States) |
| Project ID | NIH-11141566 on NIH RePORTER |
What this research studies
Our bodies, much like plants, respond to light cues from the environment, which influence how we grow and function. This research looks closely at special proteins called cryptochromes, which act like light sensors in both plants and humans. By understanding how these proteins work in plants to control growth and development, we can learn more about their similar roles in human processes. This knowledge could help us better understand how our own bodies regulate important functions like sleep-wake cycles and metabolism.
Who could benefit from this research
Good fit: This foundational biological work does not directly involve patient participation, but future studies building on this knowledge might seek individuals with conditions related to circadian rhythm disorders or metabolic issues.
Not a fit: Patients seeking immediate treatment options or direct clinical interventions would not find direct benefit from this basic science research.
Why it matters
Potential benefit: Understanding how cryptochromes work could lead to new insights into human conditions related to circadian rhythms, metabolism, and potentially even cancer, as these proteins are present in humans.
How similar studies have performed: While the specific mechanisms of cryptochromes are still being uncovered, the general concept of light influencing biological processes is well-established across many organisms.
Where this research is happening
Cold Spring Harbor, United States
- Cold Spring Harbor Laboratory — Cold Spring Harbor, United States (Active)
Researchers
- Principal investigator: Pedmale, Vincent U — Cold Spring Harbor Laboratory
- Study coordinator: Pedmale, Vincent U
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.