How light affects pupil control in the visual system
Downstream Actions of Biophysical Mechanisms in the Visual System
This study is looking at how light affects the size of the pupil in mice, helping us understand how our eyes adjust to different lighting for better vision.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10868463 on NIH RePORTER |
What this research studies
This research investigates how sensory signals, specifically light, influence the control of the pupil in mammals. By studying the pupillary light response, the research aims to understand the mechanisms that allow the pupil to adjust its size based on varying light conditions, which is crucial for optimal vision. The study will utilize in vivo approaches in mice to analyze retinal signals and their pathways to pupil control, employing both normal and genetically modified mice to clarify the underlying mechanisms. The findings could provide insights into how visual processing is linked to motor responses.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with visual impairments or disorders affecting pupil response.
Not a fit: Patients with stable vision and no history of visual disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of visual processing and lead to improved treatments for vision-related disorders.
How similar studies have performed: Previous research has shown success in understanding sensory signal processing in the visual system, making this approach promising yet still exploring novel aspects.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Do, Michael Tri Hoang — Boston Children's Hospital
- Study coordinator: Do, Michael Tri Hoang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.