NIH-funded research NIH-funded research

How lifestyle changes affect brain health and memory in older adults

Official title: Impact of change in lifestyle health behaviors on cognition: Harmonizing and leveraging participant-level data from randomized controlled trials

Funded at University of Illinois at Chicago · NIH-10984344 · Data updated 2026-11-12

This study is looking at how making healthier choices in diet, exercise, and social activities can help improve brain health in older adults, especially those at risk for Alzheimer's and similar conditions, to find out which changes work best for keeping their minds sharp.

More Cognition research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startSeptember 15, 2024
Project endAugust 31, 2027
Funding year2024
Award (this year)$2,366,213
NIH project number1RF1AG089550-01
Project IDNIH-10984344 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults, particularly those aged 21 and above, who are at risk for Alzheimer's disease or related dementias.

Less likely to help

Patients who are not at risk for cognitive decline or who are under 21 years old may not benefit from this research.

What this research studies

This research investigates how changes in lifestyle health behaviors, such as diet, exercise, and social engagement, can influence cognitive health in older adults, particularly those at risk for Alzheimer's disease and related dementias. By analyzing data from 12 previous randomized controlled trials involving nearly 10,000 participants, the study aims to identify which specific lifestyle changes have the most significant impact on cognitive outcomes. The goal is to provide insights that can help tailor lifestyle interventions for diverse groups of older adults to enhance their cognitive function and overall brain health.

Why it matters

Potential benefit: If successful, this research could lead to effective lifestyle interventions that help protect against cognitive decline and improve memory in older adults.

How similar studies have gone: Previous research has shown promising results in using lifestyle interventions to improve cognitive health, indicating that this approach has potential for success.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Halloway, Shannon — University of Illinois at Chicago
  • Study coordinator: Halloway, Shannon

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.