How lifestyle and genes relate to breast tissue density in Hispanic women
The impact of lifestyle and genetic factors on mammographic density in a cohort of Hispanic women
This project looks at how everyday habits and inherited genes are linked to breast tissue density in Hispanic women, a factor tied to breast cancer risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11301923 on NIH RePORTER |
What this research studies
If you take part, researchers will collect and store mammogram images from thousands of Hispanic women in a large U.S. cohort. They will measure how much dense (glandular and connective) tissue versus fatty tissue is present and calculate percent density for each mammogram. Those density measures will be linked with participants' lifestyle information (such as body weight, diet, and reproductive history) and genetic data to find patterns. The team will compare results across ages, menopausal status, and Hispanic subgroups to better understand who may have higher risk.
Who could benefit from this research
Good fit: Ideal candidates are adult Hispanic women in the U.S., especially those already enrolled in the HCHS/SOL cohort or who can provide recent mammograms and health information.
Not a fit: People who are not Hispanic, men, or women without mammograms or available genetic/lifestyle data are unlikely to directly benefit from this specific project.
Why it matters
Potential benefit: If successful, this work could improve breast cancer risk prediction and help tailor screening or prevention strategies for Hispanic women.
How similar studies have performed: Previous studies in mostly non-Hispanic White groups have shown mammographic density predicts breast cancer risk, but applying this approach specifically to Hispanic women is less tested and fills an evidence gap.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Lindstroem, Sara — University of Washington
- Study coordinator: Lindstroem, Sara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.