How lead exposure affects stress responses in children
Developmental exposure to lead and noradrenergic regulation of the acute stress response
['FUNDING_R21'] · LOUISIANA STATE UNIV A&M COL BATON ROUGE · NIH-11138938
This study is looking at how being exposed to lead when kids are young might affect how they handle stress, especially in children aged 0-11, to help us understand and find better ways to support those who may struggle with anxiety or depression later on.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOUISIANA STATE UNIV A&M COL BATON ROUGE (nih funded) |
| Locations | 1 site (BATON ROUGE, UNITED STATES) |
| Trial ID | NIH-11138938 on ClinicalTrials.gov |
What this research studies
This research investigates how exposure to lead during early development impacts the body's response to stress, particularly focusing on the role of noradrenergic signaling. By studying children aged 0-11 years, the research aims to understand the mechanisms behind behavioral changes associated with lead exposure and stress-related disorders like anxiety and depression. The approach includes examining the functioning of specific neurons that regulate stress responses and how they are affected by lead. The findings could provide insights into potential interventions for children facing these challenges.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been exposed to lead and exhibit stress-related behavioral issues.
Not a fit: Patients who are not within the age range of 0-11 years or who have not been exposed to lead may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for children suffering from anxiety and depression linked to lead exposure.
How similar studies have performed: Previous research has shown that environmental factors, including lead exposure, can significantly impact stress responses, indicating that this area of study has potential for meaningful insights.
Where this research is happening
BATON ROUGE, UNITED STATES
- LOUISIANA STATE UNIV A&M COL BATON ROUGE — BATON ROUGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABDELMONEIM, AHMED — LOUISIANA STATE UNIV A&M COL BATON ROUGE
- Study coordinator: ABDELMONEIM, AHMED
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.