How lead exposure affects brain cell interactions during development
Neuron-Astrocyte Interactions in Developmental Lead Exposure
This study is looking at how lead exposure during important growth periods affects brain cells and their communication, with the goal of finding ways to improve mental health for those who have been exposed to lead.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10674537 on NIH RePORTER |
What this research studies
This research investigates the interactions between neurons and astrocytes, a type of brain cell, in the context of developmental lead exposure. It aims to understand how lead impacts brain function and contributes to mental health disorders by examining cellular processes and signaling pathways. The study employs advanced techniques to analyze the effects of lead on brain cell communication and function, which could provide insights into the underlying mechanisms of psychiatric diseases. By focusing on individuals exposed to lead during critical developmental periods, the research seeks to uncover potential therapeutic targets for improving mental health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who have experienced lead exposure during their development.
Not a fit: Patients who have not been exposed to lead or are over 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for mental health disorders linked to lead exposure.
How similar studies have performed: Previous research has shown that understanding neuron-astrocyte interactions can lead to significant advancements in treating psychiatric disorders, indicating a promising avenue for this study.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Sampson, Maureen Mcguirk — Emory University
- Study coordinator: Sampson, Maureen Mcguirk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.