How lactation affects magnesium balance in the kidneys
Regulation of Renal Tubular Mg2+ Handling by MUC1 and Lactation
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11049600
This study looks at how breastfeeding affects the way your kidneys handle magnesium, which is important for your health, especially since your body might need more during this time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-11049600 on ClinicalTrials.gov |
What this research studies
This research investigates how lactation influences the kidneys' ability to manage magnesium levels in the body. It aims to uncover the mechanisms that regulate magnesium excretion through the kidneys during lactation, a time when magnesium stores can be depleted. By studying changes at the systemic, tissue, cellular, and molecular levels, the research will explore how lactation affects gene expression and kidney function related to magnesium absorption. This could provide insights into how to better manage magnesium levels in lactating individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are lactating women who may be experiencing magnesium deficiency or related health issues.
Not a fit: Patients who are not lactating or those with pre-existing kidney conditions unrelated to magnesium handling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing magnesium deficiency in lactating women, potentially enhancing bone health and overall well-being.
How similar studies have performed: While the specific mechanisms of lactation-associated magnesium conservation are not extensively studied, related research has shown promising results in understanding mineral balance during physiological changes.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAY, EVAN CROSS — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: RAY, EVAN CROSS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.