How lack of sleep and depression affect memory in adolescents

The role of insufficient sleep and depression on hippocampal-dependent memory trajectories across the adolescent transition

['FUNDING_CAREER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10926844

This study looks at how not getting enough sleep and feeling depressed can affect memory development in teenagers, with the goal of finding ways to help improve their mental health and learning.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-10926844 on ClinicalTrials.gov

What this research studies

This research investigates the impact of insufficient sleep and depression on memory development during adolescence. It focuses on understanding how these factors influence hippocampal-dependent memory, which is crucial for learning and cognitive function. The study aims to identify the mechanisms behind memory deficits associated with depression and poor sleep, particularly during the critical transition from childhood to adolescence. By examining these relationships, the research seeks to inform potential interventions that could improve mental health and cognitive outcomes in young people.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 9 to 12 years who are experiencing symptoms of depression and sleep disturbances.

Not a fit: Patients who are not in the adolescent age range or do not experience sleep issues or depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing memory and mental health in adolescents facing sleep issues and depression.

How similar studies have performed: Previous research has indicated that sleep quality and mental health significantly affect cognitive functions, suggesting that this study's approach is grounded in established findings.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.