NIH-funded research NIH-funded research

How lack of sleep affects emotional control and brain function

Official title: The Impact of Insufficient Sleep and Insomnia Disorder on Behavioral and Neural Markers of Emotion Regulation

Funded at Beth Israel Deaconess Medical Center · NIH-11090358 · Data updated 2026-11-12

This study looks at how not getting enough sleep or having insomnia affects how people manage their emotions, comparing those with insomnia to healthy individuals who also struggle with sleep, to better understand how sleep problems can impact emotional well-being.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center
NIH-funded
Lab location1 site (Boston, United States)
Project startJune 15, 2022
Project endMay 31, 2027
Funding year2025
Award (this year)$158,231
NIH project number5K23MH127464-04
Project IDNIH-11090358 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults aged 21 and older who experience insomnia or chronic sleep deprivation.

Less likely to help

Patients who do not have sleep disturbances or emotional regulation issues may not benefit from this research.

What this research studies

This research investigates the effects of insufficient sleep and insomnia on how individuals regulate their emotions. It aims to understand the differences in emotional responses between those with clinical insomnia and healthy individuals who experience multiple nights of inadequate sleep. By examining behavioral and neural markers during emotion regulation tasks, the study seeks to uncover the underlying mechanisms that link sleep disruption to emotional dysregulation. This research is particularly important as it addresses a significant gap in knowledge regarding the chronic effects of sleep loss on emotional health.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for emotional disorders linked to sleep issues.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between sleep and emotional regulation, but this study aims to explore a less tested chronic sleep disruption model.

Where this research is happening

  • Beth Israel Deaconess Medical Center
    Boston, United States
    Active

Researchers

  • Principal investigator: Cunningham, Tony J — Beth Israel Deaconess Medical Center
  • Study coordinator: Cunningham, Tony J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.