How irregular sleep schedules affect heart and metabolic health
The role of irregular sleep schedules as a ubiquitous marker of chronic circadian disruption in cardiometabolic disease development
This study looks at how having irregular sleep patterns might affect your heart and metabolic health, like increasing the risk of high blood pressure, diabetes, and heart disease, and it’s for anyone interested in how sleep habits can impact overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10889087 on NIH RePORTER |
What this research studies
This research investigates the impact of irregular sleep patterns on the development of heart and metabolic diseases. By analyzing data from over 92,000 participants in the UK Biobank, the study aims to identify how variations in sleep schedules relate to conditions like hypertension, diabetes, and cardiovascular disease. It will also explore whether certain demographic factors influence these relationships and assess if maintaining regular sleep can mitigate genetic risks for these diseases. The findings could provide insights into how lifestyle changes can improve health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing irregular sleep patterns or those at risk for cardiometabolic diseases.
Not a fit: Patients with stable and regular sleep schedules may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing heart and metabolic diseases through improved sleep habits.
How similar studies have performed: Previous studies have shown that circadian rhythm disruptions can impact health, but this research aims to expand understanding to a broader population, making it a novel approach.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Redline, Susan S. — Brigham and Women's Hospital
- Study coordinator: Redline, Susan S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.