How intestinal worms affect HPV and cervical health in women.
Impact of intestinal helminth infection on HPV co-infection and the cervico-vaginal environment.
This study is looking at how intestinal worm infections might affect the presence of HPV in adult women in Peru, to better understand their connection and help find ways to reduce the risk of cervical cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11004082 on NIH RePORTER |
What this research studies
This research investigates the relationship between intestinal helminth infections and human papillomavirus (HPV) co-infections in adult women. By conducting a cross-sectional study in Peru, the research aims to evaluate the prevalence of HPV, analyze cervico-vaginal cytokine profiles, and assess the microbiota in women with and without intestinal helminth infections. The findings could provide insights into how these infections influence cervical cancer risk and inform potential interventions for prevention.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult women undergoing cervical cancer screening, particularly those living in low- and middle-income countries with high rates of intestinal helminth infections.
Not a fit: Patients who do not have intestinal helminth infections or are not at risk for HPV-related cervical cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cervical cancer in women living in low-resource settings.
How similar studies have performed: Preliminary data suggest a significant association between intestinal helminth infections and HPV, indicating that this research builds on existing findings but explores a novel aspect of the relationship.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Clark, Eva H — Baylor College of Medicine
- Study coordinator: Clark, Eva H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.