How internal states affect decision-making in the brain
State-dependent Decision-making in Brainwide Neural Circuits
This study looks at how the feelings and needs of mice affect the choices they make, helping us understand the brain processes behind their decisions as they learn and engage in different tasks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906270 on NIH RePORTER |
What this research studies
This research investigates how an animal's internal state influences its decision-making processes, particularly in mice. By examining various internal state changes, such as engagement in tasks and learning over time, the study aims to uncover the neural mechanisms behind these decisions. The research employs advanced techniques, including simultaneous recordings from multiple neurons and computational modeling, to analyze brain activity and behavior. This collaborative effort leverages the expertise of a consortium to achieve its ambitious goals.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions that impact decision-making and behavior.
Not a fit: Patients who do not have behavioral or decision-making disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of decision-making processes, potentially informing treatments for disorders that affect behavior.
How similar studies have performed: Other research has shown success in understanding decision-making processes through similar approaches, indicating a promising avenue for further exploration.
Where this research is happening
New York, United States
- Columbia Univ New York Morningside — New York, United States (Active)
Researchers
- Principal investigator: Paninski, Liam M — Columbia Univ New York Morningside
- Study coordinator: Paninski, Liam M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.