How intermittent fasting can improve lipid metabolism and health
Beneficial reprogramming of lipid metabolism with intermittent fasting
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10830426
This study is looking at how taking breaks from eating, known as intermittent fasting, can help improve heart health and metabolism, especially for people who are overweight, without having to stick to a strict diet every day.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10830426 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of intermittent fasting on lipid metabolism and overall cardiometabolic health. It aims to understand how fasting can provide benefits similar to caloric restriction without the need for daily adherence to a strict diet. By analyzing metabolic responses through clinical assessments and advanced multi-omics techniques, the study seeks to identify how fasting duration impacts health markers like weight, blood lipids, and glucose levels. The research also explores whether these benefits are more pronounced in individuals who are overweight.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in improving their metabolic health, particularly those who are overweight or have cardiometabolic conditions.
Not a fit: Patients who are underweight or have specific eating disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary strategies that improve metabolic health and potentially extend lifespan.
How similar studies have performed: Previous studies have shown promising results with intermittent fasting, indicating potential benefits similar to those of caloric restriction.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FAZELI, POUNEH KHADEJEH — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: FAZELI, POUNEH KHADEJEH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.