How insulin growth factor-like proteins affect skin inflammation
Official title: Immunomodulatory Functions of Insulin Growth Factor Like Proteins in Skin Inflammation
Funded at Rlr VA Medical Center · NIH-11054241 · Data updated 2026-11-12
This study is looking at how certain proteins in the body might affect skin allergies, like contact dermatitis and atopic dermatitis, to find better ways to treat people who have these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rlr VA Medical Center NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| NIH project number | 1I01BX006631-01A1 |
| Project ID | NIH-11054241 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults, particularly veterans and active-duty military personnel, who suffer from allergic contact dermatitis or atopic dermatitis.
✕Less likely to help
Patients with non-allergic skin conditions or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the role of insulin growth factor-like proteins in allergic skin inflammation, particularly focusing on conditions like allergic contact dermatitis and atopic dermatitis. By studying the molecular pathways involved, the research aims to identify how these proteins and their receptors contribute to skin inflammation. The approach includes using genetically modified mouse models to better understand the biological functions of these proteins and their potential as therapeutic targets. The ultimate goal is to improve treatment options and outcomes for individuals suffering from these skin conditions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for allergic skin conditions, improving the quality of life for affected patients.
How similar studies have gone: Previous research has shown promise in understanding the role of cytokines in skin inflammation, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rlr VA Medical Center
Indianapolis, United States Active
Researchers
- Principal investigator: Turner, Matthew J — Rlr VA Medical Center
- Study coordinator: Turner, Matthew J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.