How Insulin Affects Cell Stability
Investigation of the role of insulin receptor in chromosome stability.
This project explores how insulin's signals help keep our cells' genetic material stable, which is important for preventing diseases like type 2 diabetes and cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11093564 on NIH RePORTER |
What this research studies
Our bodies use insulin not just for managing sugar, but also as a growth factor that helps cells multiply. This project explores how the insulin receptor, found on many cell types, sends signals that are crucial for cell health and growth. We want to understand how these signals help maintain the stability of our chromosomes, the structures that carry our genetic information. This knowledge is vital because too much insulin is linked to conditions like type 2 diabetes and cancer. By learning more about this process, we hope to uncover new ways to prevent or treat these diseases.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation, but future studies building on this work may seek individuals with type 2 diabetes or certain cancers.
Not a fit: Patients seeking immediate treatment or direct clinical intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: This work could lead to a better understanding of how insulin contributes to diseases like type 2 diabetes and cancer, potentially opening doors for new prevention or treatment strategies.
How similar studies have performed: This project builds upon recent findings from the research team, suggesting a novel connection between insulin signaling and chromosome stability.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Choi, Eunhee — Columbia University Health Sciences
- Study coordinator: Choi, Eunhee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.