How insomnia affects pain and inflammation in people with HIV

The Impact of Insomnia on Pain, Physical Function, and Inflammation in HIV

NIH-funded research University of Alabama at Birmingham · NIH-10453431

This study is looking at how trouble sleeping, or insomnia, affects pain and physical abilities in people living with HIV, hoping to find ways to help manage these issues better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10453431 on NIH RePORTER

What this research studies

This research investigates the relationship between insomnia and its impact on pain, physical function, and inflammation in individuals living with HIV. It aims to understand how insomnia, a common issue among this population, may worsen pain symptoms and hinder physical abilities. The study will explore the biological mechanisms, particularly inflammation, that link poor sleep to increased pain sensitivity and functional deficits. By examining these connections, the research seeks to provide insights that could lead to better management strategies for those affected.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are living with HIV and experiencing insomnia.

Not a fit: Patients who do not have HIV or those who do not experience insomnia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for managing pain and enhancing physical function in individuals living with HIV who suffer from insomnia.

How similar studies have performed: Previous research has shown that insomnia can significantly impact pain and inflammation in other populations, suggesting that this approach may yield valuable insights for individuals with HIV.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immunodeficiency SyndromeAcquired Immune Deficiency SyndromeAcquired Immuno-Deficiency SyndromeAcquired Immunologic Deficiency Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.