NIH-funded research R01 grant

How insecticide exposure affects ADHD risk in adolescents

Official title: Adolescent Insecticide Exposure and ADHD Risk: Mechanisms of Immediate Effects and Long-term Vulnerability

Funded at University of Iowa · NIH-11046512 · Data updated 2026-11-12

This study looks at how being around insecticides might affect the brains of teenagers, especially in ways that could lead to ADHD symptoms, and it focuses on young people who work with pesticides to better understand the short- and long-term effects on their brain development.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa
NIH-funded
Lab location1 site (Iowa City, United States)
Project startMarch 1, 2024
Project endFebruary 28, 2027
Funding year2025
Award (this year)$514,674
NIH project number5R01ES035696-02
Project IDNIH-11046512 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12 to 20 who have been exposed to insecticides, particularly those in agricultural settings.

Less likely to help

Patients who are not adolescents or those who have not been exposed to insecticides may not benefit from this research.

What this research studies

This research investigates the impact of insecticide exposure on the developing brains of adolescents, particularly focusing on how it may lead to symptoms of Attention Deficit Hyperactivity Disorder (ADHD). The study examines both immediate and long-term effects of exposure, utilizing a cohort of adolescent pesticide applicators who experience higher levels of insecticide exposure. By analyzing neurobehavioral performance and potential biological mechanisms, the research aims to uncover how these exposures influence brain development and functioning during a critical growth period. The findings could help identify vulnerable populations and inform preventive measures.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of ADHD symptoms linked to environmental exposures in adolescents.

How similar studies have gone: Previous research has indicated potential links between environmental exposures and neurobehavioral outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

  • University of Iowa
    Iowa City, United States
    Active

Researchers

  • Principal investigator: Stevens, Hanna E — University of Iowa
  • Study coordinator: Stevens, Hanna E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.