NIH-funded research R01 grant

How inner ear changes affect balance and fall risk as we age

Official title: Towards healthy aging: Quantifying vestibular contributors to age-related changes in balance and fall risk

Funded at Ohio State University · NIH-11134712 · Data updated 2026-11-12

This project looks at whether age-related changes in the inner ear make balance worse and raise the chance of falling for older adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 30, 2021
Project endMay 31, 2027
Funding year2025
Award (this year)$701,080
NIH project number5R01AG073113-05
Project IDNIH-11134712 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults, especially older adults with balance problems or a history of falls, who can come for balance and vestibular testing.

Less likely to help

People whose balance issues are clearly due to non-vestibular causes (for example, advanced neuropathy or severe musculoskeletal limitations) may not directly benefit from vestibular-focused findings.

What this research studies

You may be invited to have simple balance tests (for example, standing with eyes closed on foam) and measurements of inner-ear (vestibular) sensitivity. The team will combine new measurements with large existing datasets and use modern statistical methods to estimate how much vestibular changes explain age-related balance loss and fall risk. Their goal is to link age, vestibular precision, balance performance, and reported falls to identify the most important contributors. Findings will help point to who might benefit from targeted prevention or treatment strategies.

Why it matters

Potential benefit: If successful, this work could identify inner-ear problems that contribute to falls and guide more focused fall-prevention strategies for older adults.

How similar studies have gone: Prior analyses have already shown strong links—one reported that vestibular measures explained nearly half of age-related balance decline and national survey data linked failed balance tests to higher odds of falling—so this approach builds on promising, but not yet fully translated, findings.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Merfeld, Daniel M — Ohio State University
  • Study coordinator: Merfeld, Daniel M

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.