How infections and climate change affect the stability of our gut microbes
Determinants of Microbiome Stability Following Pathogen Infection
This study is looking at how things like infections and climate change affect the balance of good bacteria in our gut, which is important for our health, and it aims to find ways to help these bacteria stay strong and healthy during tough times.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-10890823 on NIH RePORTER |
What this research studies
This research investigates how disturbances like infections and climate change impact the stability of the human microbiome, which is crucial for our health. It aims to understand how the diversity and composition of gut microbes influence their ability to remain stable during infections. By examining these factors, the research seeks to identify ways to enhance microbiome resilience, potentially leading to better health outcomes. The study will utilize various methodologies, including DNA sequencing, to analyze microbial changes in response to environmental stressors.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced recent infections or significant environmental changes affecting their health.
Not a fit: Patients with stable microbiomes and no history of infections or environmental stressors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining gut health during infections and environmental changes.
How similar studies have performed: Previous research has shown promising results in understanding microbiome dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Jani, Andrea — University of Hawaii at Manoa
- Study coordinator: Jani, Andrea
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.