How increased transposition affects aging
Genetic and genomic effects of increased transposition
['FUNDING_R01'] · BRANDEIS UNIVERSITY · NIH-10855751
This study is looking at how certain genetic elements in fruit flies might affect aging and age-related diseases, hoping to uncover new insights that could help us understand why we age and how to stay healthier as we get older.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRANDEIS UNIVERSITY (nih funded) |
| Locations | 1 site (WALTHAM, UNITED STATES) |
| Trial ID | NIH-10855751 on ClinicalTrials.gov |
What this research studies
This research investigates the role of retrotransposon activity in the aging process using Drosophila, a fruit fly model. By examining how the expression of retrotransposon mRNA changes with age, the study aims to determine whether this activity contributes to aging and age-related diseases. The researchers will utilize genetic tools and established observations in Drosophila to explore the molecular mechanisms behind aging. This approach could provide insights into the biological processes that underlie lifespan and health decline as organisms age.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of aging and those affected by age-related conditions.
Not a fit: Patients who are not experiencing age-related diseases or conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for understanding and potentially mitigating age-related diseases.
How similar studies have performed: While the specific approach of examining retrotransposon activity in aging is novel, similar studies have successfully used Drosophila to uncover important biological insights into aging.
Where this research is happening
WALTHAM, UNITED STATES
- BRANDEIS UNIVERSITY — WALTHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARR, MICHAEL THOMAS — BRANDEIS UNIVERSITY
- Study coordinator: MARR, MICHAEL THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.