How immune cells help heal skin wounds
Mechanisms of immune-epithelial crosstalk in tissue repair
This study looks at how certain immune cells help skin cells heal wounds, aiming to find out why some wounds don’t heal well and how we can use this knowledge to make healing better for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11178611 on NIH RePORTER |
What this research studies
This research investigates the interactions between immune cells and skin cells during the healing process of wounds. It focuses on understanding how specific immune cell types, particularly type 17 cells, contribute to the activation of skin cells that are essential for repairing tissue damage. By studying these mechanisms in detail, the research aims to uncover new insights into why some wounds fail to heal and how immune signals can be harnessed to improve healing outcomes. The approach includes systematic ablation of immune cell types in animal models to observe their effects on skin repair.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic wounds or conditions that impair skin healing.
Not a fit: Patients with acute wounds or those without any underlying conditions affecting healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance wound healing and reduce the incidence of chronic wounds.
How similar studies have performed: Other research has shown promising results in understanding immune cell roles in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Naik, Shruti — Icahn School of Medicine at Mount Sinai
- Study coordinator: Naik, Shruti
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.