How hydrogen sulfide affects blood vessel function
Regulation of H2S signaling in vascular function
This study is looking at how a gas called hydrogen sulfide helps control blood flow in our bodies, especially how it works in different sizes of blood vessels, to find new ways to improve heart health and treat conditions that affect blood flow.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10880397 on NIH RePORTER |
What this research studies
This research investigates the role of hydrogen sulfide (H2S) in regulating blood flow and vascular function, particularly focusing on how endothelial cells (ECs) produce H2S and its effects on different types of blood vessels. The study aims to understand the mechanisms behind H2S signaling and its potential to improve blood flow regulation, which is crucial for preventing cardiovascular diseases. By examining the differences in how H2S affects small and large arteries, the research seeks to uncover new insights into vascular health and disease. Patients may benefit from findings that could lead to new treatments for conditions related to impaired blood flow.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular diseases or conditions that affect blood flow regulation.
Not a fit: Patients with non-cardiovascular related health issues or those without any vascular dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for improving blood flow and preventing cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding the role of gasotransmitters like H2S in vascular function, indicating that this approach has potential for significant findings.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Naik, Jay S — University of New Mexico Health Scis Ctr
- Study coordinator: Naik, Jay S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.