How humidity and heat shape malaria risk in cities

Redefining thermal suitability for urban malaria transmission in the context of humidity

['FUNDING_R01'] · CORNELL UNIVERSITY · NIH-11409082

This project looks at how humidity together with temperature changes the chance of malaria for people living in cities with urban mosquitoes.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCORNELL UNIVERSITY (nih funded)
Locations1 site (ITHACA, UNITED STATES)
Trial IDNIH-11409082 on ClinicalTrials.gov

What this research studies

This work combines laboratory tests on urban malaria mosquitoes, historical and real-time weather data, and computer models to see how humidity alters temperature-driven transmission. Scientists will measure mosquito survival and biting under different heat-and-humidity conditions and use those results to update transmission models. The project focuses on urban-adapted mosquitoes like Anopheles stephensi in South Asia and on preparing for possible spread into African cities. Improved models and maps aim to identify city neighborhoods and times of year with higher malaria risk so control can be targeted.

Who could benefit from this research

Good fit: People living in or near cities where urban malaria mosquitoes are present—especially in South Asia and parts of Africa—are the most likely to benefit or be asked to provide data.

Not a fit: People in rural areas where different mosquito species drive malaria or those far from urban transmission zones are less likely to see direct benefits.

Why it matters

Potential benefit: If successful, the work could give health authorities clearer, location-specific warnings and control plans that reduce malaria cases in cities.

How similar studies have performed: Models using temperature to explain malaria seasonality have been useful, but humidity's quantitative role is much less tested, so this project builds on established methods while adding new, understudied factors.

Where this research is happening

ITHACA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.