How Human Papillomavirus (HPV) Infects Cells
Human papillomavirus entry: late trafficking and establishment of infection
['FUNDING_R01'] · LOUISIANA STATE UNIV HSC SHREVEPORT · NIH-11125760
This research helps us understand the detailed steps of how human papillomavirus (HPV) enters and infects our cells, which is important for developing new ways to prevent or treat HPV-related conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOUISIANA STATE UNIV HSC SHREVEPORT (nih funded) |
| Locations | 1 site (SHREVEPORT, UNITED STATES) |
| Trial ID | NIH-11125760 on ClinicalTrials.gov |
What this research studies
Our cells have many internal structures, and this project looks closely at how HPV moves through these structures to establish an infection. We are learning that the virus uses a specific pathway involving the cell's transport system and even takes advantage of cell division to reach the nucleus. By studying the tiny 'motor proteins' that help the virus move, we hope to uncover new ways to stop HPV from infecting cells. This work builds on recent discoveries about how the virus navigates inside cells.
Who could benefit from this research
Good fit: This foundational laboratory research does not involve direct patient participation, but future clinical applications could benefit individuals affected by HPV infections or related cancers.
Not a fit: Patients will not receive direct medical benefit from participating in this specific laboratory-based research.
Why it matters
Potential benefit: Understanding the precise mechanisms of HPV infection could lead to the development of more effective antiviral treatments or improved vaccines to prevent HPV-related diseases.
How similar studies have performed: Previous findings in this area have been confirmed by other researchers using advanced imaging techniques, suggesting a solid foundation for this work.
Where this research is happening
SHREVEPORT, UNITED STATES
- LOUISIANA STATE UNIV HSC SHREVEPORT — SHREVEPORT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZWOLINSKA, KATARZYNA — LOUISIANA STATE UNIV HSC SHREVEPORT
- Study coordinator: ZWOLINSKA, KATARZYNA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.