How human evolution affects genetic traits and diversity
Human evolution and the genetic architecture of complex traits
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11090638
This study looks at how our genes change over time and how that affects our traits, helping us understand more about genetic diversity and health, which could be useful for people with different backgrounds.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11090638 on ClinicalTrials.gov |
What this research studies
This research investigates how evolutionary forces influence genetic variation and phenotypic traits in human populations. It explores the impact of recessive deleterious alleles and associative overdominance, moving beyond traditional racial classifications to focus on genetic relatedness. By utilizing advanced computational models and simulation tools, the study aims to understand complex traits and their interactions. Patients may benefit from insights into genetic diversity and health outcomes based on their genetic background.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who are interested in the genetic factors influencing their health.
Not a fit: Patients with no interest in genetic research or those from highly homogeneous populations may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic diversity and its implications for health and disease in different populations.
How similar studies have performed: Other research has shown success in understanding genetic variation through evolutionary perspectives, indicating that this approach has potential for meaningful insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HERNANDEZ, RYAN D. — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: HERNANDEZ, RYAN D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.