How hormones affect eating behavior and obesity
Rapid hormonal modulation of feeding circuit dynamics and its disruption in obesity
This study looks at how eating a lot of carbs affects the brain's hunger signals and how this changes when someone is obese, hoping to understand how our gut and brain work together to make us feel full or hungry.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11034092 on NIH RePORTER |
What this research studies
This research investigates how carbohydrate-rich diets influence the brain's feeding circuits and how these processes are altered in obesity. By studying the communication between the gut and the brain, the research aims to uncover the mechanisms that regulate feelings of fullness and hunger. The approach involves using animal models to observe the effects of nutrient delivery on specific neurons in the hypothalamus that control appetite. The findings could provide insights into the biological factors contributing to obesity and potential interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or those interested in understanding the biological factors influencing their eating behaviors.
Not a fit: Patients who are not affected by obesity or those with eating disorders unrelated to hormonal regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing obesity and improving dietary habits.
How similar studies have performed: Previous research has shown promising results in understanding gut-brain communication and its impact on appetite regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Beutler, Lisa R — Northwestern University at Chicago
- Study coordinator: Beutler, Lisa R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.