How hormone receptors influence cell growth and cancer progression
Hormone Receptor Regulation of RNA Polymerase III
This study is looking at how certain hormone receptors affect the production of small molecules that help our cells make proteins, which could lead to new ways to understand and treat cancer and other conditions related to cell growth and aging.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10862754 on NIH RePORTER |
What this research studies
This research investigates the role of steroid hormone receptors in regulating RNA Polymerase III, which is crucial for producing small RNAs that help translate genetic information into proteins. By understanding how these receptors interact with gene regulation, the research aims to uncover new insights into cell growth, aging, and cancer development. The approach involves studying the mechanisms of hormone action and their effects on cell function, particularly in relation to cancer treatment. Patients may benefit from advancements in therapies targeting these pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with hormone-sensitive cancers or those experiencing age-related health issues.
Not a fit: Patients with non-hormone-related cancers or conditions unrelated to hormone receptor activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatments by targeting hormone receptor pathways.
How similar studies have performed: Previous research has shown promising results in understanding hormone receptor mechanisms, suggesting potential for breakthroughs in cancer treatment.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Sartorius, Carol Ann — University of Colorado Denver
- Study coordinator: Sartorius, Carol Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.