How hormonal contraceptives affect stress and depression
Regulation of stress and depression by hormonal contraceptives
This study is looking at how birth control pills might affect stress and feelings of sadness by examining changes in the brain of mice, which could help us understand why some people feel different when using these contraceptives.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10824648 on NIH RePORTER |
What this research studies
This research investigates the effects of hormonal contraceptives, specifically oral contraceptives, on stress and depression. Using a mouse model, the study aims to understand how these contraceptives influence the hypothalamic-pituitary-adrenal (HPA) axis, which is crucial in regulating stress responses. The researchers will explore the biochemical and molecular changes that occur in the brain, particularly focusing on receptors that manage stress and mood. By integrating various scientific techniques, the project seeks to uncover the mechanisms behind the mood-related side effects experienced by some contraceptive users.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who use hormonal contraceptives and experience mood-related side effects such as depression or anxiety.
Not a fit: Patients who do not use hormonal contraceptives or those who do not experience mood-related side effects may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of mood-related side effects in individuals using hormonal contraceptives.
How similar studies have performed: Previous research has indicated that hormonal contraceptives can affect mood and stress responses, suggesting that this investigation builds on established findings.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Schuh, Kristen — University of Michigan at Ann Arbor
- Study coordinator: Schuh, Kristen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.