How HIV treatment affects appetite and weight in postpartum women and their infants
Official title: Appetite regulation with DTG based ART in postpartum women living with HIV and their infants (Ar-DART)
Funded at Johns Hopkins University · NIH-10838916 · Data updated 2026-11-12
This study is looking at how a specific HIV treatment called Dolutegravir affects the appetite and weight of new moms living with HIV, as well as how it impacts the growth and health of their babies, to help find better ways to support both mothers and their children.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 6, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $262,105 |
| NIH project number | 1R21HD114520-01 |
| Project ID | NIH-10838916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are postpartum women living with HIV who are on DTG-based antiretroviral therapy.
✕Less likely to help
Patients who are not postpartum or those who are not living with HIV may not receive any benefit from this research.
What this research studies
This research investigates the effects of Dolutegravir (DTG)-based antiretroviral therapy on appetite regulation and body weight in postpartum women living with HIV. The study aims to understand how these treatments influence weight retention and appetite, which are critical for preventing future health issues like obesity and non-communicable diseases. Additionally, it will explore the impact of maternal DTG treatment on the growth and body composition of their infants, particularly those exposed to HIV. By leveraging existing data from mother-infant pairs, the research seeks to identify potential interventions to improve health outcomes for both mothers and their children.
Why it matters
Potential benefit: If successful, this research could lead to improved management of weight and appetite in postpartum women living with HIV, ultimately reducing their risk of obesity and related health issues.
How similar studies have gone: Previous research has shown promising results in understanding the effects of antiretroviral therapies on weight and appetite, making this study a valuable continuation of that work.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Aizire, Jim — Johns Hopkins University
- Study coordinator: Aizire, Jim
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.