How HIV exposure affects tuberculosis in young children
Official title: The relationship between HIV exposure, contact networks, and TB in children under 5 years old
Funded at Boston Medical Center · NIH-11007797 · Data updated 2026-11-12
This study looks at how being around adults with HIV might affect the chances of young children getting tuberculosis (TB), helping us find better ways to keep these kids safe and healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $193,316 |
| NIH project number | 1K23AI186597-01 |
| Project ID | NIH-11007797 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children under five years old who are either HIV-exposed or living in households with adults infected with HIV.
✕Less likely to help
Patients who are older than five years or those without any exposure to HIV may not benefit from this research.
What this research studies
This research investigates the connection between HIV exposure and tuberculosis (TB) in children under five years old. It aims to understand how adult HIV infection influences the networks of contacts that children have, which may affect their risk of contracting TB. By analyzing data from a large pediatric TB database and using social network analysis, the study seeks to identify patterns of TB transmission among children, particularly those who are exposed to HIV but not infected. The findings could help improve TB detection and prevention strategies for vulnerable children.
Why it matters
Potential benefit: If successful, this research could lead to better identification and treatment of TB in young children, ultimately reducing mortality rates.
How similar studies have gone: Previous research has shown that understanding contact networks can improve disease detection and management, suggesting this approach may yield valuable insights.
Where this research is happening
-
Boston Medical Center
Boston, United States Active
Researchers
- Principal investigator: Campbell, Jeffrey Ian — Boston Medical Center
- Study coordinator: Campbell, Jeffrey Ian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.