How HIV affects the spread and mutation of the COVID-19 virus
The effect of HIV on SARS-CoV-2 transmission and emergence of variants of concern
This study is looking at how having HIV might affect how long someone can carry the COVID-19 virus and whether that could lead to new variants, so we can better understand and manage the spread of COVID-19, especially in communities with a lot of HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11144019 on NIH RePORTER |
What this research studies
This research investigates the relationship between HIV infection and the transmission of SARS-CoV-2, the virus responsible for COVID-19. It focuses on how individuals with weakened immune systems due to HIV may carry the virus longer and potentially contribute to the emergence of new variants. By analyzing genomic data and clinical information, the study aims to understand the dynamics of viral evolution in populations with high HIV prevalence. This could help inform public health strategies to control COVID-19 spread.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who may be at risk for prolonged SARS-CoV-2 infection.
Not a fit: Patients who do not have HIV or are not at risk for severe COVID-19 infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing COVID-19 transmission in individuals living with HIV.
How similar studies have performed: Previous research has indicated that chronic infections can lead to viral mutations, suggesting that this approach may yield valuable insights.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Shin, Sanghyuk Sam — University of California-Irvine
- Study coordinator: Shin, Sanghyuk Sam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.