How histamine helps the body adapt to exercise
Histamine as a Molecular Transducer of Adaptation to Exercise
This study is looking at how a chemical called histamine, which your body releases when you exercise, helps improve your heart health and metabolism, so we can better understand how it supports the benefits of working out.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oregon NIH-funded |
| Lab location | 1 site (Eugene, United States) |
| Project ID | NIH-11075780 on NIH RePORTER |
What this research studies
This research investigates the role of histamine, a chemical released during exercise, in promoting health benefits related to physical activity. It aims to understand how histamine affects various bodily functions, including cardiovascular health and metabolism, by examining its release from muscle cells during exercise. The study will explore the mechanisms behind histamine's effects and how it contributes to positive adaptations in the body from aerobic exercise training.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who engage in regular aerobic exercise and are interested in understanding how their bodies adapt to physical activity.
Not a fit: Patients who are sedentary or unable to participate in aerobic exercise may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing exercise benefits and improving overall health.
How similar studies have performed: Previous research has indicated that understanding molecular mechanisms like histamine can significantly enhance our knowledge of exercise physiology, suggesting potential for success in this area.
Where this research is happening
Eugene, United States
- University of Oregon — Eugene, United States (Active)
Researchers
- Principal investigator: Halliwill, John R. — University of Oregon
- Study coordinator: Halliwill, John R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.