How high fructose and salt diets affect heart and kidney health
Impact of Dietary Fructose and High Salt Diet on Neurocardiovascular and Renal Function
This study is looking at how eating a lot of sugar and salt affects your heart and kidneys, especially if it can lead to high blood pressure and stiff blood vessels, so we can find early signs of these problems and help prevent serious health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-11061041 on NIH RePORTER |
What this research studies
This research investigates the impact of diets high in fructose and salt on heart and kidney function, particularly focusing on how these dietary factors contribute to hypertension and vascular stiffness. The study aims to understand the mechanisms behind these effects, including the role of sympathetic nerve activity and the renin-angiotensin system. By examining these relationships, the research seeks to identify early indicators of vascular stiffness, which could lead to timely interventions to prevent serious cardiovascular and kidney-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults who consume high levels of fructose and salt and are at risk for hypertension or kidney disease.
Not a fit: Patients who do not consume high fructose or salt diets or those without risk factors for hypertension or kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better dietary recommendations and interventions that reduce the risk of hypertension and chronic kidney disease in patients.
How similar studies have performed: Previous research has shown that dietary factors can significantly impact cardiovascular health, suggesting that this approach may yield valuable insights.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Rossi, Noreen F — Wayne State University
- Study coordinator: Rossi, Noreen F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.