How high-fat diets and alcohol consumption affect binge behaviors and metabolism
Cross sensitization of diet and alcohol on binge behaviors and metabolic dysfunction
['FUNDING_R01'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-10670928
This study is looking at how eating a lot of fatty foods and drinking alcohol might lead to overeating and heavy drinking, and it's using mice to understand how these habits affect our body's sugar and insulin levels.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded) |
| Locations | 1 site (HERSHEY, UNITED STATES) |
| Trial ID | NIH-10670928 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between high-fat diets and alcohol consumption, focusing on how these factors may lead to binge eating and drinking behaviors. Using mouse models, the study aims to explore the neural mechanisms that link obesity and alcoholism, particularly how these behaviors affect insulin and glucose metabolism. By examining the interactions between diet and alcohol, the research seeks to uncover the underlying neurocircuitry involved in these patterns of consumption and their impact on metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who experience binge eating or drinking behaviors, particularly those with obesity or alcohol use disorders.
Not a fit: Patients who do not struggle with binge eating or drinking behaviors, or those without obesity or alcohol use disorders, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment strategies for individuals struggling with obesity and alcohol use disorders.
How similar studies have performed: Previous research has shown promising results in understanding the links between diet and alcohol consumption, suggesting that this approach could yield valuable insights.
Where this research is happening
HERSHEY, UNITED STATES
- PENNSYLVANIA STATE UNIV HERSHEY MED CTR — HERSHEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SILBERMAN, YUVAL — PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- Study coordinator: SILBERMAN, YUVAL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.