NIH-funded research R01 grant

How heavy cannabis use affects thinking and HIV prevention in young Black sexual minority men

Official title: Heavy cannabis use, neurocognition and PrEP care engagement among young Black sexual minority men

Funded at University of Chicago · NIH-11402104 · Data updated 2026-11-12

This project looks at whether heavy cannabis use changes thinking and decision-making and how that affects taking HIV prevention medicine (PrEP) among young Black sexual minority men.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$62,320
NIH project number3R01DA057351-04S1
Project IDNIH-11402104 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are young Black sexual minority men who live or receive services on Chicago's South Side, especially those who use cannabis.

Less likely to help

People who are not Black sexual minority men, who live outside the Chicago area, or who are not engaged with PrEP-related services are unlikely to benefit directly from participating.

What this research studies

You will be asked about your cannabis use, sexual behavior, and PrEP care, and may complete tests of thinking, decision-making, and other brain-related assessments. The researchers will combine your reports and test results with records of PrEP engagement and HIV prevention services over time. Recruitment focuses on young Black sexual minority men on the South Side of Chicago through local health department and CDC-supported programs. The team aims to see whether cannabis-related changes in thinking help explain who starts and stays on PrEP.

Why it matters

Potential benefit: If successful, the work could help programs better support people who use cannabis so more at-risk individuals start and stay on PrEP.

How similar studies have gone: Prior studies have linked heavy cannabis use to risky sexual behavior and cognitive changes, but using these findings to improve PrEP participation is still relatively new.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Schneider, John — University of Chicago
  • Study coordinator: Schneider, John

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.